Agents of SHIELD -OFFICIALLY returns for SEASON 3

According to Forbes and also SHIELD 's Twitter account
AGENTS of SHIELD will return for a 3rd season and almost assured its longevity

Without watching the season finale this coming tuesday what are your thought on the upcoming 3rd season
We know the potential tie in to the Civil War also the Inhumans

But what else......what other loose ends and or potential new threats should SHIELD face?